Quantitative metabolomics with validated standard protocols on high-resolution mass spectrometers

Available On Demand
 

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Quantitative metabolomics with validated standard protocols on high-resolution mass spectrometers

Available On Demand
 

Overview

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Metabolomics, crucial for understanding biological interactions, faces challenges due to a lack of standardized protocols. Addressing this, the biocrates AbsoluteIDQ p400 HR kit offers a ready-to-use, quantitative protocol targeting 408 metabolites across 11 compound classes and includes calibration, internal standards, and quality controls.

This webcast will describe how use of this targeted quantitative approach has now been validated for the Thermo Scientific Orbitrap Exploris family of mass spectrometers. Assessment using NIST SRM 1950 and human plasma samples demonstrates accuracy and reproducibility. Its applications span high-throughput analyses for large cohorts, drug discovery, and biomarker research, notably in neuroscience and cancer.

You will learn:
  • How targeted metabolomics can be applied on high resolution instruments
  • How standardization in metabolomics improves reproducibility across experiments and laboratories
  • How absolute quantification aids in data interpretation
This webcast has been produced by Thermo Fisher Scientific who retain sole responsibility for content. About this content.

Presenters

Presenter
Stephen Dearth
Senior Applications Specialist
biocrates life sciences
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Presenter
Moderator: Nikki Forrester
Freelance science
writer and editor
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