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Armor CAR T cells with enhanced potency for cancer immunotherapy

Tuesday April 8th 2025

08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.

Discover how the differentiation status of nonactivated CAR T cells can improve therapeutic efficacy of cancer immunotherapy. In this webinar, the University of Pennsylvania’s Dr. Saba Ghassemi, will discuss strategies for enhanced CAR T cell persistence and function, for better, more durable anti-tumor responses. She will explore how metabolic engineering strategies and cytokine expression can enhance CAR T cell survival, persistence, and function in challenging conditions such as the tumor microenvironment.

Attend this webinar to learn about tools that provide deep insights into CAR T cell potency via real-time, label-free tracking of tumor killing. Additionally, discover how nonactivated CAR T cells can improve CAR T longevity and therapeutic efficacy.

Attend this webinar to learn about:

  • How real-time, label-free tracking with the Axion BioSystems Maestro Z enables continuous monitoring of tumor killing dynamics, allowing for the evaluation of different CAR T cell engineering strategies
  • The role of maintaining a stem-like phenotype in nonactivated CAR T cells can lead to enhanced persistence, metabolic fitness, and long-term effectiveness
  • Improving CAR T therapeutic efficacy through metabolic reprogramming strategies
  • Enhancing CAR T survival and function in the TME with cytokine expression and metabolic fitness optimization

Presenters:

Presenter
Saba Ghassemi, PhD
Assistant Professor, Center for Cellular Immunotherapies
University of Pennsylvania
View Biography
Presenter
Charlotte Barker
Editor
BioInsights