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Optimizing RNA encapsulation is vital for formulation development and maximizing delivery to target cells to ensure the success of therapeutics and vaccines. However, assessing the efficiency of the optimization process remains challenging. One solution is single particle analyses using technologies like nano-flow cytometry. This technology makes it possible to simultaneously size and count lipid nanoparticles (LNPs) whilst identifying the presence of cargo or surface modifications to determine efficacy of the nanoparticle loading or functionalization.

In this GEN webinar, Ben Peacock, PhD, will present the NanoAnalyzer platform and describe how it supports multi-parameter analysis and characterization of biological nanoparticles like LNPs. During the webinar, you’ll learn how technology can be used to identify priority subpopulations within samples using exogenous labeling techniques, and how this allows for quantifying RNA cargo or the surface density of various targeting modalities.

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert speaker.