Laboratory-Based Drug Screening for Personalized Therapy

Previously Aired on March 31st, 2021

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Overview

Classifying tumors by organ, such as breast or brain, ignores the genetic, biologic, and patient-related factors that make cancer cases unique. Cancer therapy is therefore moving from a one-size-fits-all paradigm to one of greater personalization. Using an in-house established platform, based on an assembly of benchtop instruments, researchers in the Remke Lab at the University of Dusseldorf Medical School have developed a system that will help guide oncologists toward the right treatments, at the right time, for the right patients.

Based on quantitative, high-throughput screening, this approach will help to uncover optimal treatment choices from libraries of approved and late development-stage anticancer drugs. This highly sensitive, cell-based screening platform allows low-volume, multiple-concentration assays to support informed decision-making. The ultimate goal of this research is to enable truly personalized treatment regimens for life-threatening cancers.

In this webinar you’ll learn about:

• A drug screening method suitable for use on patient-derived primary cancer cells

• Assay miniaturization, to 384- and 1,536-well plates using benchtop instruments

• Data analysis and visualization using Python

Who should attend:

• Cancer researchers

• Translational medical researchers

• Pharmacogenomic researchers

• Cell biologists

Presenters

Presenter
Dr. rer. medic. Nan Qin
(Presenter)
PostDoc
Department of Pediatric Oncology,
Hematology, and Clinical Immunology,
Medical Faculty, University Hospital Düsseldorf
View Biography
Presenter
Tamlyn Oliver
(Moderator)
Managing Editor
Biocompare
View Biography