Multimodal single cell analysis
Friday November 22, 2019
12 pm – 1 pm EST
By probing single cells for both their transcriptome and select proteins, methods such as CITE-seq offer a rich picture of cellular function and heterogeneity.
Peter Smibert from The New York Genome Center will take listeners through a brief history of single cell analysis and discuss the methodological challenges of multimodal analysis at the single cell level. He will also provide an outlook of what the field needs to expand and how to deepen the modalities that can be probed and the insights these approaches will permit.
Ranit Kedmi from New York University School of Medicine uses CITE-seq in her work studying the interplay between T cells and the gut microbiome. She will discuss applications for which probing both mRNAs and proteins is essential and present data that could not have been obtained with unimodal approaches.
Drs Smibert and Kedmi will answer listeners’ questions on the ins and outs of methods like CITE-seq and their possible applications.

