TDM of Antibiotics Webinar

Available to View On Demand.

Antibiotic resistance is becoming an ever-growing threat to healthcare delivery. Both the antibiotic misuse and insufficient dosing are the main reasons for resistance emergence. Given the lack of novel antibiotics under development, optimized drug exposure is essential to suppress the spread of antibiotic resistance.

In the past therapeutic drug monitoring (TDM) has been employed only for antimicrobials with narrow therapeutic ranges, such as aminoglycosides. However, in recent years the knowledge about the altered pharmacokinetics in critically ill patients has led to a paradigm shift. Nowadays TDM of antibiotics is also advocated as a tool to guide dosage, ameliorating adequate drug exposure and therapeutic success in patients with severe infection, and at the same time minimizing the antimicrobial resistance. Accordingly, antibiotic TMD is becoming more widespread and increasingly recognized as a core element of hospital antibiotic stewardship programs.

This webinar reviews the basal requirements, indications and practical aspects for rational antibiotic TDM in the intensive-care setting, with a special focus on the beta-lactams that are the most widely used antibiotic class. Quantification techniques and respective bottlenecks for affordable de-centralized testing are also discussed.

Overview:

Antimicrobial resistance: a threat to global health
Pharmacokinetic/Pharmacodynamic (PK/PD) target attainment
The paradigm shift of antibiotic therapeutic drug monitoring (TDM)
Antibiotic stewardship (ABS): Rational antibiotic TDM in severe illness
Quantification techniques
Limited services for antibiotic TDM: future challenges

Michael Paal

Medical and Scientific employee
Institute of Laboratory Medicine University Hospital, LMU Munich, Germany.

Moderator: Anthony Newman

Senior Publisher
Elsevier, The Netherlands – publisher of the MSACL journal Clinical Mass Spectrometry

Registration details:

First Name *

* Required

Last Name *

* Required

Job Title *

* Required

Company/Organization *

* Required

State/Province *

* Required

Country *

* Required

Postal Code *

* Required

Email *

* Required

Work Phone *

* Required

When you register for this webinar, your contact details will be passed to the sponsor who will provide you with information relevant to this topic.

* Required

opt-out

Elsevier B.V., will use your email address to send important customer updates and product notifications. Elsevier B.V., may also occasionally contact you to share the latest updates about our other products, services, promotions, and events that may benefit you. If you do not wish to receive such messages, please check this box. You can unsubscribe or change your preferences at any time.* Required

Our registration process uses cookies, by submitting this registration form you agree to our cookie policy.

(*) denotes required form field(s)

Submit