Faster analysis of human proteomes enabled by narrow-window data-independent acquisition

Scaling proteomics with the Thermo Scientific Orbitrap Astral mass spectrometer


Available On Demand
 

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Faster analysis of human proteomes enabled by narrow-window data-independent acquisition

Scaling proteomics with the Thermo Scientific Orbitrap Astral mass spectrometer


Available On Demand
 

Overview

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This webcast will introduce the new ultra-fast scanning Orbitrap Astral mass spectrometer for comprehensive and high-throughput quantitative proteomics.

The performance of the new instrument is evaluated using narrow-window data-independent acquisition (DIA) in combination with short LC gradients. The narrow-window DIA allows acquisition of comprehensive human proteomes in a few hours, with comparable depth to next-generation RNA sequencing and with 10x higher throughput compared to the current state-of-the-art.

Optimization of instrument acquisition parameters for comprehensive proteome coverage with high quantitative precision and accuracy, as well as high-throughput biomedical applications, will be demonstrated.

Learn:
  • Quantitative performance of the Orbitrap Astral mass spectrometer for data-independent acquisition
  • Benefits of narrow-window data-independent acquisition (DIA)
  • How to acquire comprehensive human proteomes within hours

This webcast has been produced by Thermo Fisher Scientific, who retails sole responsibility for content. About this content.

Presenters

Presenter
Dr. Jesper V. Olsen
Professor, Deputy Center Director
University of Copenhagen
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Presenter
Moderator: Nikki Forrester
Freelance science
writer and editor
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