We will introduce our newly launched concept called “iVC”, which our highly advanced vitamin C derivatives. “iVC” is our original vitamin C derivative, compromising of three “i” features: “intelligent”, “innovative”, and “impressive”. Under this, we will introduce the product name, Amitose HGA, which has a high brightening efficacy thanks to melanin transport suppression and melanin degradation by the activation of autophagy, a recycle system of unnecessary and dysfunctional components. Recently, we discovered that skin glycation activates the melanin uptake into keratinocyte from melanocyte and glycated skin showed decline of melanin degradation ability. Amitose HGA has anti-glycation efficacy and it suppresses the accumulation of melanin in keratinocyte. Amitose HGA is the world’s first vitamin C derivative which suppresses skin spot pigmentation related to “autophagy” and “anti-glycation” and, we will highlight why this is an important and excellent ingredient for future formulations.