Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics
September 23rd 2020, 08:00 PDT; 11:00 EDT; 16:00 BST; 17:00 CEST
The successful clinical application of antibody-based therapeutics initially triggered the generation of various high-throughput and reliable antibody discovery platforms, each with its own unique advantages.
Today, as the immuno-oncology field strives to develop the next wave of safe, efficacious antibody therapeutics, the question has become: how can we best leverage these tools and approaches to maximize the potential for success in both translational and clinical R&D?
During this webinar, ImmunoPrecise Antibodies (IPA) will present a case study exploring the high-throughput identification of genetically distinct, target-specific antibodies as the driving force behind a streamlined, end-to-end antibody discovery and development pipeline. A multi-stakeholder panel including industry experts and a leading immuno-oncology clinician will then discuss key considerations for novel antibody therapeutic research from the clinical development perspective.
Attendees will discover:
- How to run a solid and strong antibody discovery campaign in a relatively short timeframe.
- The direct correlation between the success of a complex antibody discovery campaign, the robustness of the antibody discovery technologies used, and optimized developability analysis.
- How to overcome tolerance issues, allowing for more reliable preclinical evaluation of lead candidates without reliance on surrogate antibodies.
- Keys to preparing for translational and clinical success with novel antibody-based therapeutic technologies.

Dana-Farber Cancer Institute
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